Doc to CEO – 40 years of reinvention in biopharma
Every now and then you meet someone whose career just blows you away — not just for what they’ve achieved, but for how grounded they are about it.
Dr Stephen Dilly has spent almost 40 years in the biopharma industry and 20 of those as a CEO. He’s led two companies to billion dollar exits, run development at Genentech during the launch of game changing drugs, and now leads Codexis into its next phase. But you’d never know it from how humble, thoughtful and self-aware he is.
When I sat down with Stephen, I walked away with three big lessons.
What I Learnt
Success and humility can coexist. Stephen talks openly about failure, luck and learning — his view that we’re all “works in progress” resonated deeply with me.
Values matter more than strategy. His belief in guiding principles, and his habit of spending real time with his team each month, are the bedrock of how he leads.
Reinvention is power. From doctor to CEO, from UK to California, Stephen’s career is built on curiosity, courage and never standing still. He says you should live in the world you’re in, not the one you wish you were in — wise words for any leader.
What I Liked
Stephen is crazy impressive, yet so humble and likeable. There’s a lightness about him — a mix of wisdom and humour that puts you instantly at ease. I loved his be better than yesterday mentality, his emphasis on in-person connection, and his ability to stay curious after four decades of success. And as a Brit in North America myself, it was great to see another British leader thriving here.
Reflection
What stuck with me most was his attitude towards growth. Even after decades at the top, he still approaches leadership as a student, not a master. That humility, combined with a relentless drive to improve, is exactly what defines great leaders in this industry.
Hear the full episode here: Apple | Spotify
Big thanks to our amazing sponsors Bora Pharmaceuticals, Charles River Laboratories and Lead Candidate for supporting the pod